Journal Paper

1. "Comparison of the efficiency of the Sec and Tat secretory pathways in the secretion of recombinant neurturin protein using de novo designed signal peptides"
   Zahra Hajihassan, Mina Yazdi, Atiyeh Fadaei, Noshin Akbarsemnani
   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, Vol. ****, pp.1-13, 2024
2. "Engineering a CEACAM1 Variant with the Increased Binding Affinity to TIM-3 Receptor"
   Zahra Hajihassan, Mehran Mohammadpoursaray, Aysan Yaseri
   IRANIAN BIOMEDICAL JOURNAL, Vol. 27, No 4, pp.191-198, 2023
3. "Magnetically purification/immobilization of poly histidine-tagged proteins by PEGylated magnetic graphene oxide nanocomposites"
   Ehteram Sadat Khataminezhad, Zahra Hajihassan, Fatemeh Razi Astaraei
   PROTEIN EXPRESSION AND PURIFICATION, Vol. 207, No 106264, 2023
4. "In silico engineering a CD80 variant with increased affinity to CTLA-4 and decreased affinity to CD28 for optimized cancer immunotherapy"
   Zahra Hajihassan, Nesa Pesaran Afsharian, Naser Ansari-Pour
   JOURNAL OF IMMUNOLOGICAL METHODS, Vol. 513, No 113425, 2023
5. "Identification of new potent agonists for toll-like receptor 8 by virtual screening methods, molecular dynamics simulation, and MM-GBSA"
   Farideh Sadeghkhani, Zahra Hajihassan, Sajjad Gharaghani
   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, Vol. ****, pp.1-11, 2022
6. "Engineering a variant of IL-17RA with high binding affinity to IL-17A for optimized immunotherapy"
   Fatemeh Armaghan, Zahra Hajihassan
   Biotechnology Reports, Vol. 32, 2021
7. "De Novo Designing a Novel Signal Peptide for Secretion of Neurturin to the Periplasmic Space of Escherichia coli"
   Mina Maleki, Zahra Hajihassan
   APPLIED BIOCHEMISTRY AND MICROBIOLOGY, Vol. 57, 2021
8. "Improved Production of Recombinant Human Activin A in Escherichia coli"
   Zahra Hajihassan, Navid Nazari, Fatemeh Armaghan
   Journal of Sciences, Islamic Republic of Iran, Vol. 32, No 3, 2021
9. "Denovo designing: a novel signal peptide for tat translocation pathway to transport activin A to the periplasmic space of E. coli"
   Farshid Zandsalimi, Zahra Hajihassan, Roghaye Hamidi
   BIOTECHNOLOGY LETTERS, Vol. 42, No 1, pp.45-55, 2019
10. "Enhanced periplasmic expression of human activin A in Escherichia coli using a modified signal peptide"
    Zahra Hajihassan, Niloofar Khairkhah, Farshid Zandsalimi
    PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, Vol. 50, No 2, pp.141-147, 2019
11. "Co-expression of recombinant human nerve growth factor with trigger factor chaperone in E. coli"
    Seyedeh Mahdieh Sadat, Zahra Hajihassan, Mohammad Barshan Tashnizi, Mehri Abdi
    nova biologica reperta, Vol. 5, No 3, pp.221-228, 2018
12. "Improved Production of Recombinant Human β-NGF in Escherichia coli – a Bioreactor Scale Study"
    Zahra Hajihassan, Pouria Gholami Tilko, Seyedeh Mahdieh Sadat
    Polish Journal of Microbiology, Vol. 67, No 3, pp.355-363, 2018
13. "A Novel Signal Peptide Derived from Bacillus Licheniformis α-Amylase Efficiently Targets Recombinant Human Activin A to the Periplasm of Escherichia coli"
    Zahra Hajihassan, Seyed Kazem Hosseini, Alireza Zomorodipour
    Journal of Cell and Molecular Research, Vol. 10, No 1, pp.47-51, 2018
14. "Evaluation of Anticancer Activity of Extracted Flavonoids from Morus Alba Leaves and its interaction with DNA"
    Soudabeh Fallah, Zahra Hajihassan, Nasrin Zarkar, Azra Rabbani-chadegani, Javad Mohammadnejad Arough, Milad Hajimirzamohammad
    BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, Vol. 61, No 18160623, 2018
15. "Enhanced Expression of Recombinant Activin A in Escherichia coli by Optimization of Induction Parameters"
    Zahra Hajihassan, Nahid Biroonro
    Journal of Sciences, Islamic Republic of Iran, Vol. 29, No 2, 2018
16. "Optimization of recombinant β-NGF purification using immobilized metal affinity chromatography"
    Zahra Hajihassan, Mehri Abdi, Elaheh Roshani Yasaghi, Azra Rabbani-chadegani
    MINERVA BIOTECNOLOGICA, Vol. 29, No 3, 2017
17. "Cytotoxicity Effects of Flavonoid Extract of Morus alba Leaves in Hela Cell Line"
    Soudabeh Fallah , Zahra Hajihassan, Asie Sadeghi
    Asian Journal of Biological Sciences, Vol. 10, No 2, pp.72-79, 2017
18. "Optimization of recombinant β-NGF expression in Escherichia coli using response surface methodology"
    Pouria Gholami Tilko, Zahra Hajihassan, Hamid Moghimi
    PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, Vol. 1, No 1, pp.1-8, 2016
19. "Expression of Human Nerve Growth Factor β and Bacterial Protein Disulfide Isomerase (DsbA) as a Fusion Protein (DsbA::hNGF) Significantly Enhances Periplasmic Production of hNGF β in Escherichia coli"
    Zahra Hajihassan, Mona Sohrabi, Masoumeh Rajabi Bazl, Haniehsadat Eftekhary
    Romanian Biotechnological Letters, Vol. 21, No 5, 2016
20. "studies on the interaction of mitoxantrone with core histone proteins"
    Zahra Hajihassan, Azra Rabbani-chadegani
    Iranian Journal of Biotechnology, Vol. 11, No 42, 2013
21. "chromatin as a target for anti cancer drugs"
    Zahra Hajihassan, Azra Rabbani-chadegani
    Iranian Journal of Biotechnology, Vol. 11, No 42, pp.401-402, 2013
22. "The effect of mitoxantrone as an anticancer drug on hepatocytes nuclei and chromatin : Selective release of histone proteins"
    Zahra Hajihassan, Azra Rabbani-chadegani
    INDIAN JOURNAL OF PHARMACOLOGY, Vol. 43, No 2, pp.187-191, 2011
23. "Interaction of mitoxantrone as an anticancer drug with chromatin proteins core histones and H1 in solution"
    Zahra Hajihassan, Azra Rabbani-chadegani
    International Journal of Biological Macromolecules, Vol. 48, No 1, pp.87-92, 2010
24. "studies on the binding affinity of anticancer drug mitoxantrone to chromatin DNA and histone proteins"
    Zahra Hajihassan, Azra Rabbani-chadegani
    JOURNAL OF BIOMEDICAL SCIENCE, Vol. 16, No 1, pp.1-31, 2009
25. "The effect of vinca alkaloid anticancer drug on chromatin and histone proteins in solution"
    Azra Rabbani-chadegani, Elham Chamani , Zahra Hajihassan
    EUROPEAN JOURNAL OF PHARMACOLOGY, Vol. 613, No 3, pp.34-38, 2009
26. "The effect of cytoplasmic chaperones co-expression with recombinant human nerve growth factor in E. coli"
    Seyedeh Mahdieh Sadat, Zahra Hajihassan, Mohammad Barshan Tashnizi
    Modares Journal of Biotechnology, Vol. 12, No 3, 2021
27. "Cloning of human growth factor Activin A and the effects of cytoplasmic chaperons co-expression with it"
    Orod Ghavimi, Zahra Hajihassan, Fatemeh Armaghan
    Modares Journal of Biotechnology, Vol. 12, No 2, pp.103-119, 2021
28. "Target Mutation of CD80 Protein to Enhance Its Binding to CD28 Receptor"
    Nesa Pesaran Afsharian, Zahra Hajihassan, Naser Ansari Pour
    Modares Journal of Biotechnology, Vol. 11, No 1, 2020
29. "Magnetotactic bacteria and their applications"
    Mina Maleki, Mohammad Pooya Naghshbandi, Zahra Hajihassan
    nova biologica reperta, Vol. 6, No 4, 2020
30. "Cloning and secretory expression of human β-NGF using the modified signal peptide of the Iranian native bacillus licheniformis alpha amylase"
    Samaneh Qobadi Nasr, Zahra Hajihassan, Naser Ansari Pour
    Journal of Cell and Molecular Research, Vol. 32, No 3, pp.423-437, 2019
31. "Increased expression of recombinant activin A using optimized cell culture medium"
    Zahra Hajihassan, Navid Nazari
    Applied Biology, Vol. 32, No 2, 2019
32. "Optimization of recombinant β-NGF production in bioreactor"
    Zahra Hajihassan, Seyedeh Mahdieh Sadat, Pouria Gholami Tilko
    Modares Journal of Biotechnology, Vol. 10, No 1, pp.9-13, 2018
33. "Optimization of the effective factors in E.coli growth producing recombinant β-NGF using response surface methodology"
    Pouria Gholami Tilko, Zahra Hajihassan, Navid Nazari, Hamid Moghimi
    Modares Journal of Biotechnology, Vol. 8, No 2, 2017
34. "codon optimization and comparison of recombinant human b.NGF expression in BL21(DE3) plysS and BL21(DE3) bacterial hosts"
    Mona Sohrabi, Zahra Hajihassan, Masoumeh Rajabi Bazl
    Applied Biology, Vol. 30, No 4, pp.97-110, 2017
35. "Codon Optimization and Comparing the Expression of Recombinant Human Activin A in BL21(DE3)pLysS, BL21(DE3) Rosetta gami and BL21(DE3) Bacterial Hosts"
    Zahra Hajihassan, Seyed Kazem Hosseini, Alireza Zomorodipour
    Modares Journal of Biotechnology, Vol. 7, No 2, pp.61-71, 2016
36. "Recombinant B-NGF production in E.coli using Date syrup"
    Farshid Jaberi Ansari, Zahra Hajihassan, Hasan Jalili
    Modares Journal of Biotechnology, Vol. 6, No 2, pp.1-14, 2015
37. "Binding affinity of anticancer drug actinomycin D and mitoxantrone on rat liver chromatin"
    Zahra Hajihassan, Azra Rabbani-chadegani
    Applied Biology, Vol. 28, No 1, 2015

Conference Paper

1. "Drug design for the treatment of autoimmune diseases by increasing the binding affinity of IL-21R protein to IL-21"
   Sarah Vazifeshenas, Zahra Hajihassan, Seyed Shahriar Arab
   The 12th National Conference and the 3rd International Bioinformatics Conference, 2024
2. "Design of a mutant protein with increased binding affinity for IL-22"
   Fatemeh zahra Askariyeh, Zahra Hajihassan, Seyed Shahriar Arab
   The 12th National Conference and the 3rd International Bioinformatics Conference, 2024
3. "optimization of induction parameters for improving Neurturin production in the periplasm of Escherichia coli"
   Aysan Yaseri, Zahra Hajihassan
   15th International Congress of Laboratory and Clinic, 2024
4. "Comparison of Neurturin protein production in three expression strains of E. coli and different culture conditions"
   Aysan Yaseri, Zahra Hajihassan
   14 th international congress of medical lab. and clinic, 2023
5. "Discovery of novel small molecular ligands for TLR8 by computational methods"
   Farideh Sadeghkhani, Zahra Hajihassan, Sajjad Gharaghani
   1st International and 10th National Iranian Conference on bioinformatics, 2022
6. "Production of bovicin HC5 in two strains of E. coli, Rosetta gami and Rosetta plysS"
   Manizheh Dastjanifarahani, Zahra Hajihassan
   Irans 22nd international virtual congress of microbiology, 2021
7. "Inhibition of CTLA-4 receptor on the surface of T cells using a recombinant protein for cancer immunotherapy"
   Zahra Hajihassan, Farideh Sadeghkhani
   21th National & 9th International Congress on Biology, 2021
8. "Comparison the effect of cytoplasmic chaperones co-expression on cytoplasmic and periplasmic production of activin A protein in E. coli"
   Zahra Hajihassan
   21th National & 9th International Congress on Biology, 2021
9. "Expression and purification of engineered IL17RA protein in E. coli"
   Fatemeh Armaghan, Zahra Hajihassan
   16th National Congress of Biochemistry and 7th International Congress of Biochemistry and Molecular Biology, 2020
10. "Comparison of recombinant IL17RA expression in two strains of E. coli ; SHuffle T7 and Rosetta-gami"
    Fatemeh Armaghan, Zahra Hajihassan
    16th National Congress of Biochemistry and 7th International Congress of Biochemistry and Molecular Biology, 2020
11. "Designing a ligand like protein for blocking of Tim-3"
    Mehran Mohammadpoursaray, Zahra Hajihassan
    4th international and 16th Iranian genetic congress, 2020
12. "Designing a receptor like to IL17RA but with higher binding affinity to IL17A in silico"
    Fatemeh Armaghan, Zahra Hajihassan
    4th international student biotechnology congress, 2019
13. "Designing a novel signal peptide for secretion of recombinant human activin A protein through the twin-arginine translocation pathway in E. coli"
    Zahra Hajihassan, Farshid Zandsalimi
    20th national and 8th international congress on biology, 2018
14. "Cloning and expression of recombinant Neurturin in E. coli"
    Mina Maleki, Zahra Hajihassan
    2nd international and 10 th national biotechnology congress of Islamic Republic of Iran, 2017
15. "The effect of mutations in position 31 of CD80 on protein stability"
    Nessa Pesaran Afsharian, Zahra Hajihassan, Naser Ansari Pour
    2nd international and 10th national biotechnology congress of Islamic republic of Iran, 2017
16. "comparison of the cytoplasmic expression of recombinant activinA in the three strains of E.coli"
    Orod Ghavimi, Zahra Hajihassan
    9th international congress of laboratory and clinic, 2017
17. "cloning and cytoplasmic expression of human activinA growth factor in E.coli"
    Orod Ghavimi, Zahra Hajihassan
    9th international congress of laboratory and clinic, 2017
18. "optimization of inducer concentration for recombinant activin A expression"
    Zahra Hajihassan, Nahid Biroonro
    the 17th international and iranian congress of microbiology, 2016
19. "Cloning and Secretory Expression of Human Activin A Growth Factor Using a New Signal Peptide in E.coli"
    Niloofar Khairkhah, Zahra Hajihassan
    2nd international and 14th Iranian genetics congres, 2016
20. "Applications of vitreoscilla hemoglobin in metabolite biosynthesis"
    Saeid Kargar, Zahra Hajihassan
    1 st congress of chemical biotechnology, 2016
21. "periplasmic production of recombinant nerve groeth factor using a new signal peptide"
    Samaneh Qobadi Nasr, Naser Ansari Pour, Zahra Hajihassan
    8th international congress of laboratory and clinic, 2016
22. "co-expression of recombinant human nerve growth factor with trigger factor chaperone in E.coli; extraction and purification"
    Mehri Abdi, Seyedeh Mahdieh Sadat, Zahra Hajihassan, Mohammad Barshan Tashnizi
    8th international congress of laboratory and clinic, 2016
23. "Effects of co-expression of cytoplasmic chaperones on expression of recombinant human nerve growth factor"
    Seyedeh Mahdieh Sadat, Mohammad Barshan Tashnizi, Zahra Hajihassan
    The 16th International and Iranian Congress of Microbiology, 2015
24. "Production of recombinant nerve growth factor protein in E. coli using date syrup medium"
    Farshid Jaberi Ansari, Zahra Hajihassan, Hasan Jalili
    1St international and 9th national biotechnology congress of Islamic republic of Iran, 2015
25. "new strategies for poduction of recombinant proteins in Escherichia coli"
    Mona Sohrabi, Zahra Hajihassan, Masoumeh Rajabi Bazl, Faezeh Sarayloo
    2nd national congress in applied chemistry, zist, 2015
26. "production of recombinant drug, activin A, in order to use for cellular differentiation and tissue repair"
    Seyed Kazem Hosseini, Zahra Hajihassan
    7th international congress of laboratory and clinic and 1th conference of clinic virology, 2015
27. "Codon optimization and sub cloning of the gene of human growth factor Activin A"
    Seyed Kazem Hosseini, Zahra Hajihassan, Alireza Zomorrodipour
    first international and 13th iranian genetics congress, 2014
28. "Production of recombinant human β-NGF in two strains of E.coli"
    Mona Sohrabi, Zahra Hajihassan, Masoumeh Rajabi Bazl
    first international and 13th iranian genetics congress, 2014
29. "Expression study of human β-NGF in different temperatures, times and inducer concentrations"
    Mona Sohrabi, Zahra Hajihassan, Masoumeh Rajabi Bazl
    first international and 13th iranian genetics congress, 2014
30. "Bioinformatic optimization of signal peptide of Iranian native B. licheniformis alpha-amylase in order to secrete recombinant proteins"
    Seyed Kazem Hosseini, Zahra Hajihassan, Alireza Zomorrodipour
    first international and 13th iranian genetics congress, 2014
31. "production of recombinant nerve growth factor in order to use in stem cell therapy"
    Zahra Hajihassan
    6th international congress of laboratory and clinic, 2014
32. "studies on the mechanism of novantrone action as an anticancer drug on chromatin components"
    Zahra Hajihassan, Azra Rabbani-chadegani
    6th international congress of laboratory and clinic, 2014
33. "Co-expression of Disulfide Isomerase enzyme for Production of Recombinant human beta-Nerve Growth Factor with correctly formed Disulfide Bonds in Escherichia coli"
    Mona Sohrabi, Zahra Hajihassan, Masoumeh Rajabi Bazl, Faezeh Sarayloo
    21 st international iranian congress of physiology and pharmacology, 2013
34. "Periplasmic Expression and Production of Recombinant human beta-Nerve Growth Factor in Escherichia coli"
    Faezeh Sarayloo, Zahra Hajihassan, Masoumeh Rajabi Bazl, Mona Sohrabi
    21 st international iranian congress of physiology and pharmacology, 2013
35. "chromatin as a target for anti cancer drugs"
    Zahra Hajihassan, Azra Rabbani-chadegani
    13 th iranian congress of biochemistry and 5th international congress of biochemistry and molecular biology, 2013
36. "studies on the interaction of mitoxantrone with core histone proteins"
    Zahra Hajihassan, Azra Rabbani-chadegani
    13 th iranian congress of biochemistry and 5th international congress of biochemistry and molecular biology, 2013
37. "Comparison of the effect of mitoxantrone and actinomycin D on isolated rat liver chromatin"
    Zahra Hajihassan, Azra Rabbani-chadegani
    the 17 th national and 5 th international iranian biology conference, 2012
38. "A review of the application of carbon-based nanocomposites focusing on the performance of graphene nanocomposites / magnetic carbon nanotubes functionalized in biotechnology"
    احترام السادات خاتمی نژاد, Zahra Hajihassan, Fatemeh Razi Astaraei
    The second conference on the use of composites in Iranian industries, 2020
39. "Effect of the modified signal peptide of Iranian Bacillus licheniformis alpha-amylase on periplasmic expression of β-NGF in BL21 (DE3) and BL21 (DE3)plysS"
    Samaneh Qobadi Nasr, Zahra Hajihassan, Naser Ansari Pour
    2nd international and 14th Iranian genetics congress, 2016
40. "Eukaryotic proteins production in cell free expression systems"
    Niloofar Khairkhah, Zahra Hajihassan
    3th national and 1st international conference in applied research on biology, 2016
41. "Study the binding of NGF containing his tag to starch nanoparticles bound to nickel"
    Niloofar Madbeygi, Zahra Hajihassan, Jhamak Nourmohammadi Kouhanestani
    The 4th national conference on nanotechnology: from theory to application, 2016
42. "extraction and purification of recombinant human nerve growth factor produced in E.coli"
    Mehri Abdi, Zahra Hajihassan
    1th international and 9th national biotechnology congress of islamic republic of iran, 2015
43. "molecular mechanisms controlling DNA replication initiation in yeast and mammalian cells"
    Zahra Hajihassan, Yasaman Mahmoodi, Nafiseh Dabbaghi
    2nd national congress in applied chemistry, zist, 2015
44. "survey of the effects of mitoxantrone and danomycin on the histone proteins"
    Zahra Hajihassan, Azra Rabbani-chadegani
    the 17 th national and 5 th international iranian biology conference, 2012